Pursuant to section 26 of the Hazardous Substances and New Organisms Act 1996 (“Act”), the Environmental Protection Authority hereby determines the experimental gene therapy TSRA-196 and other target-primed reverse transcriptase/prime editing systems are not organisms and therefore are not new organisms for the purpose of the Act.

Dated at Wellington this 9th day of December 2025.

LYNETTE BROWNFIELD, Chair, decision-making committee of the Authority.