Pursuant to section 26 of the Hazardous Substances and New Organisms Act 1996, the Environmental Protection Authority hereby determines that replication defective Adeno-Associated Viral (AAV) vectors do not fulfil the definition of an organism detailed in the Act, and therefore are not new organisms for the purposes of the Act, and further, determines that Huntaway dogs (Canis familiaris) treated with the specific AAV2/8 vector constructs described by the applicant do not fulfil the definition of genetically modified organisms detailed in the Act and therefore are not new organisms for the purposes of the Act.

Dated at Wellington this 28th day of January 2015.

Dr JOHN TAYLOR, Chair, Decision-making Committee of the Authority.